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A Review on Bilayered Tablets

Anusha JSK and Karthik M

Bilayer tablet is the novel technology for the development of controlled release formulation. Developing a combination of two or more active pharmaceutical ingredients in a single dosage form is known as a bilayer tablet. Now a days the use of bilayered tablets has been increased. Bilayer tablet is more suitable for gradual release of two active ingredients in combination. Bilayered tablet technology helps in separating the two incompatible substances in which one layer is immediate release as loading dose and second layer is controlled/sustained release as maintenance dose. Two incompatible drugs can also be formulated into a bilayer tablet by adding an inert intermediate layer.