Rahul J
Angiogenesis is an essential process for development of blood vessels for growth and transport of the cancer cells. The following article enlightens the functionality of various drugs and therapies that aim for the treatment via pathways of regulation of angiogenesis and necrosis. Analysis and study of various drugs and therapies done by various researchers have been highlighted and exhibited along with their competency and failures listing few of which such as mesenchymal stem cells, Hybrid Liposomes (HL), angio-inhibitors and phytochemical isoliquiritigenin drugs, and also specific synthetic group of 25- OH Vitamin D to 1,25-OH Vitamin D [1,25(OH)2D] TNFα, protein drugs groups such as anti-VEGF antibodies and tyrosine kinase inhibitors, bevacizumab plus fluoropyrimidine-based chemotherapeutic drugs in inhibition of farnesyl diphosphate and various pathways in cancer treatment.
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