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Influence of Hypertension on Renal Function in Female Type 2 Diabetics and Females with Gestational Diabetes

Subbalakshmi NK , Geraldine Monteiro, Anupama N Sheila R Pai

Hypertension coexisting with diabetes or isolated is a risk factor for renal dysfunction. But in which of the condition renal function is more affected is not clear. Serum urea and creatinine were measured in five groups: Group A (Gestational diabetics, n = 45); group B (gestational hypertensive diabetics, n = 42); Group C (Hypertension in pregnancy, n = 42); Group 1 (female type 2 diabetics without hypertension, n = 29); Group 2 (female hypertensive type 2 diabetics, n =35). Serum urea was significantly higher in group C compared to group A and group B (p<0.001). Serum creatinine was significantly higher in group C compared to group A (p<0.05). Serum urea was significantly higher in group 2 compared to group 1 (p<0.01). In pregnancy renal dysfunction is mainly associated with hypertension. In female type 2 diabetics renal dysfunction is more severe while hypertension coexisting with diabetes.