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Effects of Calcium Channel Antagonists on Radial Artery by Doppler Ultrasound Measurements

Xile B, Xianghua F, Yanming F, Li L , Qingsheng W

Objectives: The effect of administration of nifedipine on vascular compliance of the radial artery in patients undergoing coronary intervention was evaluated.
Methods: A total of 60 patients was administrated of nifedipine one day pre-operation. The diameter, resistance index (RI), and systole peak velocity (SPV) of the radial artery were measured by Ultrasound-Doppler. Results: The greatest effect on RA diameter, SPV and RI was observed 5 minutes after administration of nifedipine. For baseline diameters <2.73 mm, RA diameter increased significantly compared with the baseline after 5 and 15 minutes (2.72 ± 0.19 mm vs. 2.38 ± 0.13 mm, P<0.001 and 2.69 ± 0.17 mm vs. 2.38 ± 0.13 mm, P<0.001, respectively), whereas the diameter was unchanged compared with the baseline after 30 minutes.
Conclusion: it was determined that administration of nifedipine before TRI improved function of the radial artery.